Tuesday, December 3, 2013

"Scientists inch closer to building a drug-delivering nanorobot"

Scientists have been hard at work recently to create a bio-synthetic "cage" for delivering drugs in the body. The cages are made of eight unique DNA strands that have custom sequences that once bound, form a functional portal. These temperature dependent "nanorobots" open up when warm (allowing the uptake or release of the drug) and close when cool (holding and transporting the drug). The enzyme that was transported in the study was horseradish peroxidase because of its ease to trace. The "nanocages" are made of DNA, so they can be customized to open and close at specific temperatures and carry larger and smaller substrates. The custom bio-synthetic transporters still have a lot of research that needs to be done but they could one day be used to treat diabetes, cancer, and many other issues.